The Chicago White Sox wrap up a road trip with a Sunday afternoon interleague matchup against the St. Louis Cardinals at Busch Stadium on September 13, 2026, with first pitch set for 2:15 PM ET. This is a late-season regular season contest between two franchises with long histories but very different trajectories this year — and for a White Sox club looking to close out the 2026 calendar with some momentum, every game in September carries weight. Catch the action on Chicago Sports Network or ESPN Chicago WMVP 1000 AM on the radio side.
Probable Pitchers: McGreevy Gets the Ball for St. Louis
The Cardinals are sending right-hander Michael McGreevy to the mound. McGreevy has worked his way into St. Louis's rotation and will present a challenge for a White Sox lineup that needs to be sharp against developing starters who can be unpredictable. Full season ERA and win-loss figures for McGreevy were not available heading into this preview, so the Sox will be working off scouting and recent tendencies rather than a heavy statistical book.
The White Sox have not officially announced a probable starter for this game. That TBA designation heading into a September contest is worth monitoring — whether it signals a bullpen game, a roster move, or a late decision, the pitching answer on the Chicago side will go a long way toward shaping the outcome. Keep an eye on the lineup card and any pregame roster activity.
Keys to Watch for the White Sox
- Solve the unknown: Without a confirmed Sox starter, St. Louis hitters may have a preparation advantage early. Chicago's offense needs to put pressure on McGreevy before Cardinals relievers can take over.
- Bullpen depth: If this turns into a bullpen game for the Sox, the late-inning arms will be tested on a Sunday when rosters can be stretched from a full weekend series.
- Situational hitting: Interleague road games in September demand execution with runners on base. The White Sox need to cash in opportunities against a Cardinals pitching staff playing in front of a home crowd.
- Defensive execution: Busch Stadium's natural grass surface rewards clean defensive play. Any errors or mental miscues on the road tend to get amplified in late-season games with playoff implications or positional pride on the line.
Prediction
Without a confirmed starting pitcher, the White Sox are entering this one at a structural disadvantage before the first pitch is thrown. McGreevy gives the Cardinals a known quantity on the mound, while Chicago's answer remains open. St. Louis gets the edge at home in a close, low-scoring game. That said, September baseball has a way of producing surprises, and the Sox are capable of manufacturing runs when the lineup clicks. Call it Cardinals 4, White Sox 2 — but this one is worth watching all nine innings.
